Dissolution Enhancement of Clarithromycin Using Ternary Cyclodextrin Complexation
نویسندگان
چکیده
منابع مشابه
Dissolution Rate Enhancement of Clarithromycin Using Ternary Ground Mixtures: Nanocrystal Formation
Clarithromycin (CLA), a broad-spectrum macrolide, is a poorly soluble drug with dissolution rate limited absorption. The aim of this investigation was to prepare CLA nanoparticles from a ternary ground mixture in the presence of sodium lauryl sulfate (SLS) and polyvinyl pyrrolidone (PVP) as co-grinding water-soluble compounds, in order to improve the drug dissolution rate. Different weight rati...
متن کاملDissolution Rate Enhancement of Clarithromycin Using Ternary Ground Mixtures: Nanocrystal Formation
Clarithromycin (CLA), a broad-spectrum macrolide, is a poorly soluble drug with dissolution rate limited absorption. The aim of this investigation was to prepare CLA nanoparticles from a ternary ground mixture in the presence of sodium lauryl sulfate (SLS) and polyvinyl pyrrolidone (PVP) as co-grinding water-soluble compounds, in order to improve the drug dissolution rate. Different weight rati...
متن کاملdissolution rate enhancement of clarithromycin using ternary ground mixtures: nanocrystal formation
clarithromycin (cla), a broad-spectrum macrolide, is a poorly soluble drug with dissolution rate limited absorption. the aim of this investigation was to prepare cla nanoparticles from a ternary ground mixture in the presence of sodium lauryl sulfate (sls) and polyvinyl pyrrolidone (pvp) as co-grinding water-soluble compounds, in order to improve the drug dissolution rate. different weight rati...
متن کاملDissolution Rate Enhancement of Clarithromycin Using Ternary Ground Mixtures: Nanocrystal Formation
Clarithromycin (CLA), a broad-spectrum macrolide, is a poorly soluble drug with dissolution rate limited absorption. The aim of this investigation was to prepare CLA nanoparticles from a ternary ground mixture in the presence of sodium lauryl sulfate (SLS) and polyvinyl pyrrolidone (PVP) as co-grinding water-soluble compounds, in order to improve the drug dissolution rate. Different weight rati...
متن کاملClarithromycin Dissolution Enhancement by preparation of Aqueous Nanosuspensions Using Sonoprecipitation Technique
Clarithromycin (CLM) is a member of macrolide family with broad spectrum antibiotic activity. It is practically insoluble in water and its poor solubility is pH dependent. In this study, series of nanosuspensions containing CLM and stabilizer such as HPMC, NaCMC, polysorbate 80, poloxamer 188 and polyvinyl alcohol in various ratios were prepared using sonoprecipitation method. Briefly, CLM was ...
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ژورنال
عنوان ژورنال: International Journal for Pharmaceutical Research Scholars
سال: 2018
ISSN: 2277-7873
DOI: 10.31638/ijprs.v7.i3.00047